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| Constraint from ExAC |
Expected no. variants |
Observed no. variants |
Constraint Metric |
|---|---|---|---|
| Synonymous | 114.9 | 93 | z = 1.27 |
| Missense | 202.0 | 117 | z = 2.93 |
| LoF | 8.7 | 2 | pLI = 0.37 |
| CNV | 1.7 | 4 | z = -0.44 |