Interested in working on the development of this resource? Apply here.

Gene: GZMK


GZMK
granzyme K (granzyme 3; tryptase II)
Number of variants
(Including filtered: 270)
Number of CNVs
(Including filtered: )
OMIM
GZMK
Other
Constraint
from ExAC
Expected
no. variants
Observed
no. variants
Constraint
Metric
Synonymous 35.7 49 z = -1.38
Missense 77.0 93 z = -0.89
LoF 8.7 6 pLI = 0.00
CNV 4.1 1 z = 0.62

Gene summary

(canonical transcript: ENST00000231009)

Mean coverage


Loading variants...