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Gene: SDHB


SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Number of variants
(Including filtered: 296)
Number of CNVs
(Including filtered: )
OMIM
SDHB
Other
Constraint
from ExAC
Expected
no. variants
Observed
no. variants
Constraint
Metric
Synonymous 36.8 34 z = 0.29
Missense 93.3 93 z = 0.02
LoF 15.5 5 pLI = 0.05
CNV 5.1 5 z = 0.01

Gene summary

(canonical transcript: ENST00000375499)

Mean coverage