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Gene: MARCH4


MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
Number of variants
(Including filtered: 291)
Number of CNVs
(Including filtered: )
OMIM
MARCH4
Other
Constraint
from ExAC
Expected
no. variants
Observed
no. variants
Constraint
Metric
Synonymous 67.0 80 z = -0.98
Missense 148.5 102 z = 1.87
LoF 12.4 5 pLI = 0.02
CNV 3.0 1 z = 0.43

Gene summary

(canonical transcript: ENST00000273067)

Mean coverage