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Gene: GZMA


GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Number of variants
(Including filtered: 288)
Number of CNVs
(Including filtered: )
OMIM
GZMA
Other
Constraint
from ExAC
Expected
no. variants
Observed
no. variants
Constraint
Metric
Synonymous 33.1 27 z = 0.65
Missense 80.0 96 z = -0.88
LoF 10.0 10 pLI = 0.00
CNV 4.2 0 z = 0.90

Gene summary

(canonical transcript: ENST00000274306)

Mean coverage


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