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Gene: CDKN2B


CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Number of variants
(Including filtered: 185)
Number of CNVs
(Including filtered: )
OMIM
CDKN2B
Other
Constraint
from ExAC
Expected
no. variants
Observed
no. variants
Constraint
Metric
Synonymous 41.1 25 z = 1.56
Missense 81.8 64 z = 0.96
LoF 3.5 1 pLI = 0.28
CNV 2.6 3 z = -0.08

Gene summary

(canonical transcript: ENST00000276925)

Mean coverage


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