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| Constraint from ExAC |
Expected no. variants |
Observed no. variants |
Constraint Metric |
|---|---|---|---|
| Synonymous | 45.7 | 46 | z = -0.02 |
| Missense | 106.1 | 43 | z = 3.00 |
| LoF | 6.1 | 2 | pLI = 0.18 |
| CNV | 3.6 | 0 | z = 0.81 |