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Gene: SOST


SOST
sclerostin
Number of variants
(Including filtered: 186)
Number of CNVs
(Including filtered: )
OMIM
SOST
Other
Constraint
from ExAC
Expected
no. variants
Observed
no. variants
Constraint
Metric
Synonymous 63.7 45 z = 1.46
Missense 126.1 74 z = 2.27
LoF 4.6 1 pLI = 0.38
CNV 8.1 1 z = 1.20

Gene summary

(canonical transcript: ENST00000301691)

Mean coverage


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