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Gene: GRB2


GRB2
growth factor receptor-bound protein 2
Number of variants
(Including filtered: 151)
Number of CNVs
(Including filtered: )
OMIM
GRB2
Other
Constraint
from ExAC
Expected
no. variants
Observed
no. variants
Constraint
Metric
Synonymous 40.2 26 z = 1.39
Missense 86.1 23 z = 3.33
LoF 10.6 2 pLI = 0.55
CNV 6.5 10 z = -0.42

Gene summary

(canonical transcript: ENST00000392562)

Mean coverage


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