Interested in working on the development of this resource? Apply here.
| Constraint from ExAC |
Expected no. variants |
Observed no. variants |
Constraint Metric |
|---|---|---|---|
| Synonymous | 7.5 | 4 | z = 0.80 |
| Missense | 21.1 | 25 | z = -0.42 |
| LoF | 1.0 | 0 | pLI = 0.42 |
| CNV | 4.5 | 0 | z = 0.96 |