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Constraint from ExAC |
Expected no. variants |
Observed no. variants |
Constraint Metric |
---|---|---|---|
Synonymous | 86.8 | 65 | z = 1.45 |
Missense | 198.2 | 136 | z = 2.16 |
LoF | 8.6 | 1 | pLI = 0.75 |
CNV | 1.6 | 0 | z = 0.40 |