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| Constraint from ExAC |
Expected no. variants |
Observed no. variants |
Constraint Metric |
|---|---|---|---|
| Synonymous | 49.7 | 46 | z = 0.33 |
| Missense | 129.4 | 131 | z = -0.07 |
| LoF | 12.4 | 7 | pLI = 0.00 |
| CNV | 3.9 | 1 | z = 0.59 |